Dr. Mishra’s lab has focused on the following main areas i) lipidomics; ii) proteomics/genomics iii) metabolomics; iv) antibacterial resistance mechanisms; v) interactions of mammalian platelet microbicidal proteins and platelet mediated anti-bacterial host defenses in vivo and in vitro; vi) metabolic pathway drug targets; vii) combinations of antibiotics for preventing the emergence of antibiotic resistance and viii) pathogenesis of endovascular infections. He also discovered the significance of Staphylococcal carotenoid augmented membrane fluidity/rigidity and its implications in resistance to host defense peptides and in vivo virulence in an endocarditis model. Dr. Mishra has pioneered discovering the mechanism of high level of daptomycin resistance in Streptococci.

Dr. Mishra has been reviewer of many prestigious scientific journals, academic editors of reputed journals and research grants of international grant agencies. His work has been recognized by a number of publications as well as grants funded by NIH/Merck/Cubist Pharmaceuticals. Dr. Mishra was honored by the American Society for Microbiology with a 2015 ICAAC (Interscience Conference of Antimicrobial Agents and Chemotherapy) Young Investigator Award. This award recognizes early career scientists for research excellence and potential in microbiology and infectious disease. He has contributed more than 50 research articles, reviews and chapters in peer-reviewed journals. He has mentored over 40 undergraduate, graduate, summer students including research staff during the course of his teaching and research career. He has taught undergraduate and graduate level courses of biochemistry, genetics, microbiology/immunology, biotechnology and directed research courses in medicine. He has also been involved in teaching clinical & non-clinical courses to clinical and post doc fellows.