Marc Swidergall, PhD
Dr. Swidergall is an Assistant Professor-in-Residence at the David Geffen School of Medicine at UCLA and an Investigator at the Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center. He conducts research in immunobiology to develop a detailed mechanistic understanding of innate and adaptive immune responses against fungal pathogens with an aim to devise novel strategies to improve the diagnosis and augment or supplement the current antifungal drug treatment against fungal infections.
Dr. Swidergall earned undergraduate degrees in Biology and Microbiology, and a PhD in Molecular Mycology in 2015 from the Heinrich-Heine-University in Dusseldorf, Germany. In 2017, Dr. Swidergall was awarded a prestigious Career Development Grant from the National Institutes of Health (NIH). He opened his laboratory in 2019 at the Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center.
Areas of Expertise
- Antifungal immunity
- Clinically relevant mouse models of mucosal and systemic infections
- Variety of immunological, biological, and imaging approaches to study host-pathogen interaction
Education
- BSc, Heinrich-Heine-University Dusseldorf, Germany
- MSc, Heinrich-Heine-University Dusseldorf, Germany
- PhD, Heinrich-Heine-University Dusseldorf, Germany
- Postdoctoral fellowship, Harbor-UCLA Medical Center
Publications
Notable recent publications:
- Millet N, Solis NV, Aguilar D, Lionakis MS, Wheeler RT, Jendzjowsky N, Swidergall M. IL-23 signaling prevents ferroptosis-driven renal immunopathology during candidiasis.; Nature Communications; 2022
- Millet N, Solis NV, Swidergall M. Mucosal IgA Prevents Commensal Candida albicans Dysbiosis in the Oral Cavity.; Frontiers In Immunology; 2020
- Swidergall M, Solis NV, Wang Z, Phan QT, Marshall ME, Lionakis MS, Pearlman E, Filler SG; EphA2 Is a Neutrophil Receptor for Candida albicans that Stimulates Antifungal Activity during Oropharyngeal Infection.; Cell Reports; 2019
- Swidergall M, Solis NV, Lionakis MS, Filler SG; EphA2 is an epithelial cell pattern recognition receptor for fungal β-glucans.; Nature Microbiology; 2017
A list of publications can be found here
Achievements
2023 MMSA Thomas J. Walsh Young Investigator Award
2021 American Association of Immunologists Careers in Immunology Fellowship
Dr. Swidergall's Team
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